Friday, April 13, 2012

Power of Play: Gamers Solve Molecular Protein Puzzle

Apr 11, 2012 7:11pm

In as fast as a few months, engineers can design computers that are thinner, faster, more durable and virus-resistant. Many medical researchers who presented at the annual TedMed conference held in Washington, DC, said they wish the same could be said about the human body.

?For our bodies and the medical world, we haven?t seen the same speed in innovation as we have in computing,? David Icke, CEO of the electronic systems company MC10, told the crowd at TedMed.

Certainly a medical degree has proven essential in diagnosing and treating diseases, but what if the key to some medical advances now lie in those who are armed not with a medical degree but with just a video game controller? ?That?s why engineers and researchers are throwing open the floor to, well, anyone really. That is, anyone willing to spend some time gaming.

Perhaps researchers have been looking too long at one equation that they can?t see the answers quite like a pair of fresh eyes, suggested Seth Cooper, creative director at the center for game science at the University of Washington.

So Cooper and his colleagues created?Foldit, a computer game that allows gamers to compete against each other to design proteins and fold proteins in different shapes to replicate diseases. Gamers can also design new proteins that might eventually help prevent or treat diseases.

Within three weeks of joining a team and being handed a controller, Mimi, an avid gamer from England, and an online team dispatched worldwide, discovered what researchers have spent decades trying to find. In September, Mimi and her team ? all average gamers and not medical researchers ? replicated a protein structure from within a virus that causes AIDS in monkeys.

These findings helped researchers understand the structure of HIV in humans, said Cooper, and could help them develop therapies that will help block the enzymes that could cause the virus to spread.

And equally important, Cooper said, these findings all speak to the power of play.

?We?re more willing to experiment with ideas when we?re not worried about outcome,? said Cooper.

Cooper and his colleagues started the project after finding that computer algorithms were not enough to create and reproduce protein folds that would help researchers understand exactly how diseases are formed.

?One of the key advances that humans have over computers is creativity,? said Cooper.

But what would an average gamer know about protein folds and disease modeling? In the case of Mimi and her virtual teammates, apparently everything.

Cooper said there are more gaming challenges, this time for gamers to find ways to create protein structures to inhibit the flu virus. ?Cooper said his team hopes these additional challenges will prompt more gamers to use their creativity to find more diseases and treatments.

?We can?t really predict what?s going to happen,? said Cooper.

all star weekend lent undercover boss barbara walters tupelo honey limp bizkit stations of the cross

Thursday, April 12, 2012

Ronaldo matches own goal record in Madrid win

By PAUL LOGOTHETIS

AP Sports Writer

Associated Press Sports

updated 6:35 p.m. ET April 11, 2012

MADRID (AP) -Cristiano Ronaldo matched his own Spanish league record of 40 goals in a season by netting a hat trick that included two spectacular long-range strikes as Real Madrid beat Atletico Madrid 4-1 Wednesday to restore its four-point lead over Barcelona atop the standings.

Ronaldo opened the scoring in the 25th minute by bending a stunning free kick from 40 meters (yards) out of reach of Atletico goalkeeper Thibaut Courtois before Radamel Falcao equalized with his 21st goal of the season a half hour later.

But Ronaldo used another dipping shot - this time from outside the left edge of the area - in the 68th for his second, then added a late penalty to take his season tally to 52 goals in all competitions.

Jose Callejon also scored late for Madrid, which hasn't lost a city derby since 1999 and is only three goals away from matching its 22-year-old league record of 107 in a season.

Most importantly, Madrid regained its four-point lead over three-time defending champion Barcelona, with the pair set to meet in 10 days after one more league round.

Ronaldo's 16th career hat trick marked a tremendous night at the Vicente Calderon for the 27-year-old Portugal forward, who became the first player to score 40 league goals in consecutive seasons in Europe's top leagues.

Barcelona's Lionel Messi trails Ronaldo's league tally by one, but has netted 61 goals overall this season and became the first player to score 20 away goals in a Spanish league campaign.

Atletico started brightly as it looked for its first victory in 23 games against its crosstown rival, and Iker Casillas had to deny Falcao early on before Ronaldo's long-range free kick went over Atletico's defensive wall before sharply swerving down and away to leave Courtois flat-footed and looking on in astonishment.

Ronaldo kept Courtois' busy throughout, while Casillas was also being tested. The Spain keeper was beaten by Falcao's header, which left the Colombia striker third in the league scoring charts behind Ronaldo and Messi.

Knowing another draw would give Barcelona renewed hope ahead of their April 20 matchup, Madrid pressed relentlessly and eventually wore down Atletico's resistance.

Courtois denied Ronaldo again before the former world player of the year fired a wicked shot over the outstretched Courtois that dipped under the far corner for his second goal.

Diego Godin muscled substitute Gonzalo Higuain to the ground to set up the 83rd-minute penalty which Courtois couldn't keep out despite diving the right way.

Callejon added the last goal as Madrid picked up a much needed victory ahead of Saturday's game against Sporting Gijon, while Barcelona plays at Levante.

Earlier, Europa League favorites Athletic Bilbao scored twice in the final 10 minutes to draw 2-2 at 10-man Granada, Valencia beat Rayo Vallecano 4-1 to provisionally move ahead of Malaga into third, and Sporting Gijon rallied for a 3-2 victory over Levante to move off the bottom of the standings.

? 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


advertisement

More news
Man United falls, Man City wins

Roundup: Manchester United stumbled on its path to the Premier League title, losing 1-0 at Wigan on Wednesday night and allowing Manchester City to close within five points with a 4-0 win over West Bromwich Albion.

Ronaldo matches own goal record in Madrid win

MADRID (AP) -Cristiano Ronaldo matched his own Spanish league record of 40 goals in a season by netting a hat trick that included two spectacular long-range strikes as Real Madrid beat Atletico Madrid 4-1 Wednesday to restore its four-point lead over Barcelona atop the standings.

jewelry stores sleep no more cyber monday deals war eagle war eagle pawn stars restrepo

Good Health Tips :Turbulence Training and Weight Loss | Health ...

Turbulence training can help you to burn all those excessive calories. Furthermore the program is open to people with different levels of fitness. That is the primary benefit of working with the system. Serious consideration of the turbulence training program Turbulence training can

=============
Article Content:
Turbulence training can help you to burn all those excessive calories. Furthermore the program is open to people with different levels of fitness. That is the primary benefit of working with the system.

Serious consideration of the turbulence training program

Turbulence training can be an important ally in trying to get into shape. There are different elements of the program that you can access. A training workout follows the specific patterns which are expected of you. A free video can be used to help you progress from one step to the next. The program enables you to assess the progress that you have made in terms of keeping your weight under control.

The program has been designed in order to give you access to the most important information: Turbulence training materials will be used to provide you with support directly to your email. Your personal details will be held in confidence for communication purposes only. The exercise demonstration is a complimentary package which comes with the package.

The program has been able to challenge the stereotypes: There has been some controversy concerning the fact that the program chances the metabolic rates for its readers. Boring cardio exercises are not always the answer to your weight loss objectives. This book is able to fiercely create a model that is unique in the industry. In addition the advice is provided in a very direct and personal way.

The program has email communication in order to promote its concept: According to the program you do not have to do cardio in the morning. Interval training will effectively remove all the barriers which are preventing you from making the maximum achievements on the program. The fat burning zone can be independent of cardio training. Short bursts of exercise can be incorporated in your daily routine so that you can lose weight. According to this program there is no requirement that you follow a daily schedule. You just need forty five minutes of exercise on alternative exercise.

With this program you can lose fat and gain muscle: Turbulence training allows you to lose fat and gain muscle. These achievements are within grasp if you are diligent in the way that you follow the system. In addition there are resting periods which you can use to help the body to recover. The system is based on commonsense approaches. The readers can really improve their body shape if they follow the program with some diligence. Looking at the general analysis of the program you can make healthy decisions concerning your lifestyle.

Turbulence training is able to challenge the traditional methods which are sometimes not effective. In conclusion these are the basic requirements of a good exercise program. That is one of the solutions that people have been looking for.

???????

rick perry travis barker get back on board rob lowe peyton manning what is sopa marianne gingrich ibooks author

Wednesday, April 11, 2012

Welcome to the general election: Team Obama takes on Mitt Romney (Washington Bureau)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, RSS Feeds and Widgets via Feedzilla.

facebook timeline kim jong il kim jong il vaclav havel vaclav havel kim jong ii dead snapdragon

The Oklahoma Bankruptcy Lawyers at Atkins & Markoff Alert Public to

The Oklahoma bankruptcy attorneys at Atkins amp; Markoff, whose law firm Web site URL can be found at http://www.OklahomaBankruptcyLawCenter.com, hereby alerts the public of a March 20, 2012 story in the Washington Post stating that a bill has been introduced in Congress that, if it becomes law, would allow debtors to discharge their private student loan debts in bankruptcy cases. Federal or publicly-funded student loans would still not be eligible for discharge, but such a bill could lead to billions of dollars being able to be discharged by struggling consumers.

Oklahoma City, OK (PRWEB) April 09, 2012

The Oklahoma bankruptcy lawyers at Atkins amp; Markoff hereby alert the public of a report that appeared in the Washington Post on March 20 that detailed the introduction of a bill in Congress that, if it passed and became a law, would allow people who owe private student loan debt to discharge that debt in bankruptcy cases. Those student loans that are public, or guaranteed by the government, would still not be eligible for discharge.

The bill was introduced by Senator Richard Durbin of Illinois, and the stated reasons for the introduction of this bill include the concern that student loan debt could become a ?debt bomb? that could derail the current economic recovery. According to the federal government, almost $900 billion is owed in student loan debt in the United States.

In addition to the overall number, borrowers older than 60 years of age owe a total of $36 billion in student loan debt. These debts represent loans that were taken out relatively recently as people went back to school during the recession and cosigners of loans by parents of children who are currently unable to make the payments.

In addition, statistics provided by the Federal Reserve Bank of New York reveal that more than 25 percent of all student loan borrowers in the United States currently have balances that are past-due. Finally, that same set of data provided reveal that nearly one-third of all student loan borrowers in the United States are 40 years old or older.

The Oklahoma bankruptcy lawyers at Atkins amp; Markoff have been working with consumers who needed to file for bankruptcy protection for many years, and while student loan debt still cannot be discharged, anyone who is experiencing financial trouble and who owes student loan debt should still have their financial situations reviewed by a professional.

About Atkins amp; Markoff

The Oklahoma bankruptcy lawyers at Atkins amp; Markoff, whose law firm Web site URL can be found at http://www.OklahomaBankruptcyLawCenter.com, is a law firm comprised of Oklahoma bankruptcy attorneys who have been representing consumers since 1999 in bankruptcy-related legal matters that include Chapter 7, Chapter 11 and Chapter 13 bankruptcy cases as well as debt consolidation and credit counseling matters. The firm represents consumers in bankruptcy cases throughout the state of Oklahoma.

For the original version on PRWeb visit: http://www.prweb.com/releases/prweb2012/4/prweb9379367.htm

Get Fast EZ Payday Loans Online with FastEZPayday.com, a nationwide leader in quick payday loans.

nashville weather jason varitek andrew breitbart dead sheriff joe arpaio limbaugh aaron smith wilt chamberlain

The U.S. Navy Is Hiring Video Game Console Hackers | Geekosystem

As if there wasn?t enough video game hacking out there, the U.S. Navy just arranged for a little more, and paid over $100,000 for it. No, they?re not looking to boost their kill-death ratios in MW:3 by using?wall-hacks or something. Instead, they?re hoping these hired hackers will be able to help them intercept useful inteligence that is being communicated by console messaging services. That?s right: They want to eavesdrop on terrorists who discuss their plans over a heated match of Halo: Reach.

The company that?s been awarded the contract,?Obscure Technologies, is now going to have to crack into some consoles and sniff around a little bit to see what they can salvage. The unclassified and publicly available?Statement of Work document, covers things in a little more detail. In short, Obscure is going to have to:

  • Provide monitoring for 6 new video game systems, a maximum of 2 of any type from any given vendor.
  • Generate clean data (data that does not contain any identifiable information from real people) from new video game systems.
  • Design a prototype rig for capturing data from new video game systems.
  • Implement the prototype rig on the new video game systems.
  • Provide used video games systems purchased on the open market.? Used systems provided shall be likely to contain data from previous users.
  • Extend tool development to implement creating signatures over sections.
  • Survey console chat room technology and identify potential chokepoints where data may be committed to storage.
  • Identify data storage points on used video game systems and attempt to demonstrate proof of concept.
  • Extract real data from used video game systems.

On top of all that, they?ll be required to whip up some prototype hardware and software that can be used for this kind of console hacking. The details are a bit vague, but it seems Obscure will need to deliver both a program that can scrape data from consoles?remotely, in real time, and a physical bug that can scrape information off of used systems and contiunally monitor the system it?s attached to. In return, they get?$177,237.50 and more importantly, 2 Wiis, 2 PS3s, and 2 Xboxes from the U.S. government. Bet you?re jealous.

Of course, everyone involved here is quick to say that any tactics learned from this little endeavor won?t be used on consoles belonging to U.S. citizens. Ostensibly this is a civil rights move, but I?ll bet that the U.S. government has little interest in finding out which 12-year-old has sent the most fraudulent,?misspelled?Xbox Live ban notifications. I, on the other hand, would love to know so feel free to tip me off.

(via ZDnet)

Relevant to your interests

?

sag awards 2012 nominees sag awards pro bowl 2012 roster yamaguchi road house occupy oakland occupy oakland

Harris and Hilfenhaus swing test back to Aussies

[ [ [['Titanic', 7]], 'http://news.yahoo.com/titanic-anniversary/', '[Complete coverage: The Titanic, 100 years later]', ' ', '630', ' ', ' ', ], [ [['A picture is worth a thousand words', 5]], 'http://news.yahoo.com/why-facebook-bought-instagram-4-theories-160400376.html', '[Related: Why Facebook bought Instagram: 4 theories]', ' ', '630', ' ', ' ', ], [ [['He was in shock and still strapped to his seat', 9]], 'http://contributor.yahoo.com/join/yahoonews_virginiabeach', '[Did you witness the jet crash? Share your story with Yahoo! News]', ' ', '630', ' ', ' ', ], [ [['A JetBlue flight from New York to Las Vegas', 3]], 'http://yhoo.it/GV9zpj', '[Related: View photos of the JetBlue plane in Amarillo]', ' ', '630', ' ', ' ', ], [ [['Afghan security forces and police killed three', 3]], 'http://yhoo.it/H9BcJE', '[Related: Bales\' wife on his alleged shooting: \'He would not do that\']', ' ', '630', ' ', ' ', ], [ [['He was in shock and still strapped to his seat', 6]], 'http://news.yahoo.com/photos/navy-jet-crashes-in-virginia-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120406/jet_ap.jpg', '630', ' ', 'AP', ], [ [['This is as serious of a tornado', 7]], 'http://news.yahoo.com/photos/tornadoes-touch-down-in-texas-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120403/trucksdallas.jpg', '630', ' ', 'Reuters', ], [ [['Oikos University', 8]], 'http://news.yahoo.com/photos/deadly-oakland-university-shooting-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120402/shooting.jpg', '450', ' ', 'REUTERS/Reuters TV/KNTV/Handout', ], [ [['Trayvon Martin decked the Neighborhood', 7]], 'http://yhoo.it/GUovUP', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/2/61/261d2c36bccf0971c2734a4d4398aa5a.jpeg', '512', ' ', 'AP/David Goldman', ], [ [['Few thought Santorum would make it this far', 10]], 'http://yhoo.it/I0D5eb', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/d/94/d94312dd12151943f05633f372e64d80.jpeg', '630', ' ', 'Scott Olson/Getty Images', ], [ [['xxxxxxxxxxxx', 11]], 'http://news.yahoo.com/photos/russian-grannies-win-bid-to-sing-at-eurovision-1331223625-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/1/56/156d92f2760dcd3e75bcd649a8b85fcf.jpeg', '500', ' ', 'AP', ] ]

[ [ [['because I know God protects me', 14], ['Brian Snow was at a nearby credit union', 5]], '28811216', '0' ], [ [['The state news agency RIA-Novosti quoted Rosaviatsiya', 6]], '28805461', '0' ], [ [['measure all but certain to fail in the face of bipartisan', 4]], '28771014', '0' ], [ [['matter what you do in this case', 5]], '28759848', '0' ], [ [['presume laws are constitutional', 7]], '28747556', '0' ], [ [['has destroyed 15 to 25 houses', 7]], '28744868', '0' ], [ [['short answer is yes', 7]], '28746030', '0' ], [ [['opportunity to tell the real story', 7]], '28731764', '0' ], [ [['entirely respectable way to put off the searing constitutional controversy', 7]], '28723797', '0' ], [ [['point of my campaign is that big ideas matter', 9]], '28712293', '0' ], [ [['As the standoff dragged into a second day', 7]], '28687424', '0' ], [ [['French police stepped up the search', 17]], '28667224', '0' ], [ [['Seeking to elevate his candidacy back to a general', 8]], '28660934', '0' ], [ [['The tragic story of Trayvon Martin', 4]], '28647343', '0' ], [ [['Karzai will get a chance soon to express', 8]], '28630306', '0' ], [ [['powerful storms stretching', 8]], '28493546', '0' ], [ [['basic norm that death is private', 6]], '28413590', '0' ], [ [['songwriter also saw a surge in sales for her debut album', 6]], '28413590', '1', 'Watch music videos from Whitney Houston ', 'on Yahoo! Music', 'http://music.yahoo.com' ], [ [['keyword', 99999999999999999999999]], 'videoID', '1', 'overwrite-pre-description', 'overwrite-link-string', 'overwrite-link-url' ] ]

gabrielle giffords juliette lewis chelsea handler mitch daniels elizabeth warren shirataki noodles john kerry